mobile navigation

Faculty Profiles

Faculty Profiles

Sherri  Steele

Professor

Program Coordinator of General Arts & Sciences
Professor of Life Sciences

Academic Background:

BSc – University of Guelph – Biomedical Sciences
PhD – University of Toronto – Medical Sciences

Sherri’s research interests are in neurodegeneration, specifically the neuropathology of acute, traumatic spinal cord injury.  During her graduate studies, Sherri studied the role of Fas-mediated apoptosis in the cellular and molecular injury mechanisms following cervical spinal cord injury.  This line of research included an investigation of the potential for various clinically-relevant neuroprotective agents, including a soluble Fas-receptor molecule and Immunoglobulin G (IgG) administration.  While working as a graduate student at the Toronto Western Research Institute, Sherri was given the opportunity to present her work in numerous forums including many poster presentations and several podium presentations at international conferences in the area of neuroscience and neurotrauma.

Sherri has been teaching in the area of life sciences for 7 years, starting with Laurentian University and Georgian College as a contract faculty, and for the past 5 years as a full-time faculty member here at Sheridan within the Faculty of Humanities and Social Sciences.  She has also had the pleasure of being the General Education Coordinator, and more recently took over the role of General Arts & Science Program Coordinator at Sheridan.

Publications:

Ackery, A., Robins, S. and Fehlings, MG. (2006)  Inhibition of Fas-mediated apoptosis through administration of soluble Fas receptor improves functional outcome and reduces posttraumatic axonal degeneration after acute spinal cord injury.  Journal of Neurotrauma 23(5): 604-616.

Robins, S and Fehlings, MG. (2008)  Models of experimental spinal cord injury: translational relevance and impact.  Drug Discovery Today: Disease Models, online publication.

Robins-Steele, S., Nyugen, H. and Fehlings, MG. (2012)  Delayed post-injury administration of intrathecal sFasR shows promising efficacy after cervical spinal cord injury.  Journal of Neurotrauma 29(8):1586-1599.

Notable Oral Presentations:

    May 2006 – International Neurotrauma Symposium, Rotterdam, The Netherlands
    “Neuroprotection of the Injured Spinal Cord Through Administration of a Soluble Fas     Receptor to Block Fas-Mediated Apoptosis”

November 2007 – Society for Neuroscience (SfN) Annual Meeting, San Diego CA
“Delayed glial expression of Fas/FasL contributes to secondary cell death and can be therapeutically targeted following acute spinal cord injury”

December 2007 – Cervical Spine Research Socitey (CSRS) Annual Meeting, San Francisco CA  “Delayed glial expression of Fas/FasL contributes to secondary cell death and can be therapeutically targeted following acute spinal cord injury”

Research Interests & Skills:

Neurodegeneration, neuropathology, cellular and molecular mechanisms of disease, specifically in the central nervous system.
Microsurgical techniques, tissue and cell histology including confocal & fluorescence microscopy, protein and DNA/RNA quantification methods.